Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

William S. Halsted, MD

William S. Halsted, MD
(1852 – 1922)

American anatomist, teacher, and surgeon, William Stewart Halsted was born in New York City, USA to a wealthy family of English origin. His father was involved in charitable work and Governor and trustee to a city hospital. Not a brilliant student initially, Halsted took an undergraduate in Liberal Arts in Yale, CT., after which he entered the Medical College of Physicians at the Columbia College, where he excelled.

As a second-year medical student Halsted applied and obtained a position in surgery at a local hospital. In here he learned about Lister’s antiseptic technique and became an adamant proponent of it to reduce infection. In 1877 Halsted obtained his MD. After a short time as House Physician at the New York Hospital, Halsted traveled to Europe to further his education studying for two years at the Universities of Vienna, Leipzig, and W?rzburg.

Besides being at the forefront of surgical and antiseptic techniques (introducing the use of rubber gloves in surgery), Halsted was extremely concerned with the way medical students were taught in the US. He pioneered bedside clinical round discussions with the medical students after two years of basic sciences studies. Halsted developed the idea of a patient chart; he also developed the residency program for medical students in use today.

Halsted is probably the most influential researcher and surgeon at the turn of the century. He dedicated time to the study of intestinal anastomoses and the use of silk as a suture material. His experimental work in 1887 proved that the inclusion of the submucosa layer in an anastomosis was mandatory, as well that a single layered anastomosis was enough to attain closure. Perhaps Halsted’s most important contribution was the application and use of the scientific method to surgical questions. Halsted’s principles, also known as  "Halsted's Rules of Surgery", set the standards used today in surgical suturing and surgical stapling.

He also pioneered the development and surgical techniques for radical mastectomy as a treatment for breast cancer.

As a side effect of this studied in anesthesia and the use of cocaine for anesthesia, Halsted became addicted to this substance, a problem that followed him through the years. Without impairing his capacity as a researcher and a surgeon, Halsted eventually recovered. He died in Baltimore in 1922 as a complication to surgery.

Sources:
1. Dubay, A. D., & Franz, G. M. (2003). Acute Wound Healing: The Biology of Acute Wound Failure. Surg Clin NA, 83, 463-481.
2. Halsted, W. S. (1887). Circular Suture of the Intestine - An Experimental Study. Am J Med Sci, 436-461.
3. “William Stewart Halsted: his life and contributions to surgery” Osborne, P. Lancet Oncol 2007; 8: 256–65
4. “William Stewart Halsted: Surgical pioneer” Burress, P Endoc Today (2010), 8: (2) 22
5. “William Stewart Halsted (1852–1922) Neurological stamp” Haas, LF J Neurol Neurosurg Psych 2000;69:641
Original image courtesy of "Images from the History of Medicine" at  www.nih.gov


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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Sunao Tawara, M.D.
Sunao Tawara, MD

UPDATED:  Sunao Tawara, M.D. (1873 - 1952) Sunao Tawara was born in the prefecture of Ooita, Kyushu, Japan. Adopted by an uncle (and physician), Tawara studied English and German, and went on to the University of Tokyo medical school, where he graduated an MD in 1901.

In 1903 he traveled to Marburg, Germany, where he started working under the supervision of Dr. Karl Albert Ludwig Aschoff (1866-1942), a noted pathologist. Tawara’s work led him to the discovery of what today we call the "atrioventricular node” (AV node) and the connections of the AV node and the Bundle of His  by discovering the right and left bundle branches. His work with Aschoff led to the eponym of “node of Aschoff-Tawara” for the AV node. Tawara’s work also led to the understanding of the function of the Purkinje fibers. Tawara gave the entire system the name “Reitzleitungssytem” or the “conduction system” of the heart.

In 1906 Dr. Tawara published his discoveries in a German-language article entitled “The Conduction System of the Mammalian Heart — An Anatomicopathological Study on the Atrioventricular Bundle and the Purkinje Fibers”. The same year he returned to Japan and in 1908 became Professor of Pathology at the University of Kyushu until his retirement in 1933.

Not enough honors have been given to Dr. Tawara as the discoverer of some of the main components of the conduction system of the heart, such as the atrioventricular node, the left and right bundle brunches, and establishing the connection between the Bundle of His and the Purkinje fibers. William Einthoven himself cited Tawara's work as the basis to interpret an electrocardiogram.

Sunao Tawara was the sole discoverer of the AV node. Dr. Aschoff was his academic supervisor and mentor. When Tawara published his monograph, Aschoff wrote the foreword for it. At no time did he claim co-authorship of Tawara's work. The eponym "Aschoff-Tawara" node for the atrioventricular node was accepted to recognize Aschoff's support to Tawara's work. 

Tawara's original monograph in German is available at archive.org. For the monograph, click here.

Image from Sunao Tawara MD monograph on the conduction system of the heart 
Image from Dr. Tawara's monograph

Sources:
1. "Sunao Tawara" Suma, K. Clin Cardiol (1991) 14; 442-443
2. "Sunao Tawara, A Cardiac Pathophysiologist" Loukas, M. et al Clinical Anatomy 21:2–4 (2008)
3. "Sunao Tawara: A Father of Modern Cardiology" Suma, K. J Pacing Clin Electrophysiol (2001) 24:1; 88- 96
Image of Dr. Tawara in the public domain after copyright expiration in 1970.