Dr. Franz Kaspar Hesselbach

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A Moment in History

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross

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Details: Written by: Efrain A. Miranda, Ph.D.; Published: November 18, 2013; Hits: 9411

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Franz Kaspar Hesselbach (1759 – 1816). German physician, surgeon, and anatomist. Hesselbach was born in Bavaria in 1759. At the age of 19 he became an apprentice to Karl Von Siebold (1736 - 1807), a German surgeon, obstetrician and anatomist. He worked with him as an unpaid assistant for six years until 1789 when he was hired as a prosector.

Hesselbach became a lecturer on anatomy at the University of W?rzburg and a surgical assistant at the Juliusspital at W?rzburg. Later Hesselbach became a professor of Surgery at the same university.

Hesselbach’s name is eponymically tied to many structures, most of them related to hernia, an area where he is best known. In 1806 he published a treatise on hernia (Anatomisch-chirurgische Abhandlung ?ber den Urspurng der Leistenbr?che) “Anatomical and surgical treatise on the origin of Hernias”. These structures are:

Hesselbach’s fascia: the cribriform fascia covering the saphenous hiatus of the thigh
Hesselbach’s ligament: also known as the interfoveolar ligament
Hesselbach’s triangle: site for direct inguinal hernia
Hesselbach’s hernia: a femoral hernia protruding through the cribriform fascia

Hesselbach also described the femoral hernia in 1798 and distinguished between direct and indirect inguinal hernias.

In 1807 Hesselbach’s contributions were acknowledged and he was conferred the degree of Doctor of Surgery. During his life Hesselbach published several books, treatises, and papers.

A depiction of Hesselbach has not been found (yet) so we publish an image of his eponymic “triangle”. If you click on the image, you will see an original image from Hesselbach's book.

Sosurces:
1. "Franz Kaspar Hesselbach (1759–1816): Anatomist and Surgeon" R. Shane Tubbs et al W J Surg (2008) 32:11 2527-2529
2. "Groin Hernia Anatomical and Surgical History" McClusky DA, et al Arch Surg. 2006; 141(10):1035-1042
3. "Eponyms in groin surgery" Ellis, H. Surgery (Oxford) (2006) 24:8, 257–259
4. "Franz Kaspar Hasselbach (1759–1816)" Agarwal, AK; Mukherjee, R. Indian J. Surg (2008); 70:96–98
Primary Image property of: CAA.Inc. Artist: M. Zuptich.

Dr. Franz Kaspar Hesselbach

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