Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Triangle of pain. Posterior view of the inguinal region. The triangle of pain is depicted in yellow. The blue arrow indicates the corona mortis
Image property of: CAA.Inc.Artist: M. Zuptich.

The so-called "triangle of pain" is a misnomer coined by laparoscopic hernia surgeons who observed the anatomy of the inguinofemoral region from the posterior aspect and refers to an inverted "V" shaped area which should be avoided because of the potential to damage nerves when placing staples, tacks, or sutures to anchor a mesh during a laparoscopic herniorrhaphy.

An example of a similar situation with terminology is the so-called "triangle of doom". It is also not a triangle, as it only has two boundaries. similarly, it does indicate an area where it is dangerous to place staples or sutures during laparoscopic hernia surgery.

The "triangle of pain" is an inverted "V" shaped area with its apex at the internal (deep) inguinal ring. It is bound anteriorly by the iliopubic tract / inguinal ligament and by the testicular (spermatic) vessels posteromedially. This "triangle" has no defined posterolateral boundary. although you can see it in drawings by some authors.

The reason why this area should be avoided and not place staples or sutures to anchor a hernia mesh is that there are several nerves which usually cannot be seen as they run just deep to the endoabdominopelvic fascia.These nerves can suffer damage or entrapment  when performing a laparoscopic herniorrhaphy and cause pain (hence the name of the area) as well as motor and sensory disorders.

The nerves are:

• Lateral femoral cutaneous nerve: arising from the ventral rami of L2 and L3,  this nerve provides sensory innervation to the anterior skin of the thigh

• Femoral nerve: arising from the ventral rami of L2, L3, and L4, this nerves provides motor and sensory innervation to the anterior compartment of the thigh as well as sensory branches to the hip joint

• Genitofemoral nerve:  arising from the ventral rami of L1 and L2, this nerve divides anterior to the psoas major muscle into two branches. The genital branch of the genitofemoral nerve enters the inguinal canal and provides sensory and motor innervation to the scrotum and cremaster muscle, as well as the labia majora and mons pubis. The femoral branch of the genitofemoral nerve enters the "triangle of pain" region and passes inferior to the inguinal ligament to provide sensory cutaneous innervation to the superior aspect of the thigh.

The image shows a posterior view of the inguinal region. The "triangle of pain" is depicted in yellow. The iliopubic tract / inguinal ligament is shown by a blue dotted line while the testicular vessels boundary is shown by a red dotted line. The blue arrow points to the aberrant obturator artery (Corona Mortis). 

Thanks to Steve Pearson for suggesting this term. Medical illustration by Mark J. Zuptich.

Clinical anatomy of the inguinofemoral hernias, as well as abdominal and perineal hernias are some of the lecture topics developed and delivered to the medical devices industry by Clinical Anatomy Associates, Inc. For more information Contact Us.