Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

William S. Halsted, MD

William S. Halsted, MD
(1852 – 1922)

American anatomist, teacher, and surgeon, William Stewart Halsted was born in New York City, USA to a wealthy family of English origin. His father was involved in charitable work and Governor and trustee to a city hospital. Not a brilliant student initially, Halsted took an undergraduate in Liberal Arts in Yale, CT., after which he entered the Medical College of Physicians at the Columbia College, where he excelled.

As a second-year medical student Halsted applied and obtained a position in surgery at a local hospital. In here he learned about Lister’s antiseptic technique and became an adamant proponent of it to reduce infection. In 1877 Halsted obtained his MD. After a short time as House Physician at the New York Hospital, Halsted traveled to Europe to further his education studying for two years at the Universities of Vienna, Leipzig, and W?rzburg.

Besides being at the forefront of surgical and antiseptic techniques (introducing the use of rubber gloves in surgery), Halsted was extremely concerned with the way medical students were taught in the US. He pioneered bedside clinical round discussions with the medical students after two years of basic sciences studies. Halsted developed the idea of a patient chart; he also developed the residency program for medical students in use today.

Halsted is probably the most influential researcher and surgeon at the turn of the century. He dedicated time to the study of intestinal anastomoses and the use of silk as a suture material. His experimental work in 1887 proved that the inclusion of the submucosa layer in an anastomosis was mandatory, as well that a single layered anastomosis was enough to attain closure. Perhaps Halsted’s most important contribution was the application and use of the scientific method to surgical questions. Halsted’s principles, also known as  "Halsted's Rules of Surgery", set the standards used today in surgical suturing and surgical stapling.

He also pioneered the development and surgical techniques for radical mastectomy as a treatment for breast cancer.

As a side effect of this studied in anesthesia and the use of cocaine for anesthesia, Halsted became addicted to this substance, a problem that followed him through the years. Without impairing his capacity as a researcher and a surgeon, Halsted eventually recovered. He died in Baltimore in 1922 as a complication to surgery.

Sources:
1. Dubay, A. D., & Franz, G. M. (2003). Acute Wound Healing: The Biology of Acute Wound Failure. Surg Clin NA, 83, 463-481.
2. Halsted, W. S. (1887). Circular Suture of the Intestine - An Experimental Study. Am J Med Sci, 436-461.
3. “William Stewart Halsted: his life and contributions to surgery” Osborne, P. Lancet Oncol 2007; 8: 256–65
4. “William Stewart Halsted: Surgical pioneer” Burress, P Endoc Today (2010), 8: (2) 22
5. “William Stewart Halsted (1852–1922) Neurological stamp” Haas, LF J Neurol Neurosurg Psych 2000;69:641
Original image courtesy of "Images from the History of Medicine" at  www.nih.gov


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Longitudinal section of a kidney
Click for a larger image

The [ureters] are two long, thin, bilateral muscular tubes that extend from the pelvis of the ipsilateral kidney to the posteroinferior aspect of the urinary bladder. The ureters are retroperitoneal structures and their function is the transport of urine between the kidney and the urinary bladder.

The word arises from the Greek [ουρητήρ], meaning "urinary duct". The term was originally used to denote both the urethra (in its singular form) and the ureters (in its plural form). Because of the problems using the term, the word [urethra] was created.

The ureter is composed of three layers: a mucosa, a thick muscular layer, and an adventitia. The muscular layer is itself composed of an deep longitudinal layer and a superficial circular layer formed by spiral smooth muscle fibers. In the distal portion of the ureter there is a third layer added to the ones mentioned, a thick longitudinal layer that extends into the walls of the urinary bladder. Since the ureter is a retroperitoneal organ, in the areas where the ureter is in contact with the parietal peritoneum, it can be said that the ureter presents with a fourth layer. The muscular construction of the ureters in layers allows for peristalsis that helps the flow of urine.

In the female the pelvic ureter passes just inferior to the uterine artery, as situation that surgeons refer to as "water under the bridge". Proper identification of the ureter is critical to avoid damage to this structure during a total hysterectomy. Surgeons will use the peristaltic movement of the ureter to identify it.

In its trajectory the ureters descend anterior to the psoas major muscle, pass over the pelvic brim, just anterior to the origin of the internal iliac artery, then hug the lateral pelvic wall and enter the urinary bladder from a posteroinferior aspect. As it descends the ureters receive blood supply from different arteries: renal arteries, gonadal (testicular or ovarian) arteries, aorta, common iliac arteries, and the inferior vesical arteries.

The ureters receive sympathetic and parasympathetic innervation from the autonomic nervous system renal plexus. Pieretti (2018) described the presence of intramural neuronal bodies (ganglionated plexi) within the ureter. 

The image shows the longitudinal section of a kidney. 1-Renal pyramid, 3-Renal artery, 4-Renal vein, 5-Renal hilum, 6-Renal pelvis, 7- Ureter, 8-Minor calyx, 9-Renal capsule, 14-Minor calyx, 15- Major calyx, 16-Renal papilla, 17-Renal column .

Sources
1. "Gray's Anatomy"38th British Ed. Churchill Livingstone 1995
2. "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
3. "The origin of Medical Terms" Skinner, AH, 1970
4. "Histology; a Text and Atlas" Ross MH 3rd Ed. Williams and Wilkins 1995
Images in the public domain, courtesy of 
Wikipedia