Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Lumbar vertebra - lateral view
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The lumbar region of the spine is composed by five lumbar vertebrae. Although sharing characteristics common to all vertebrae, a lumbar vertebra can be differentiated by the following:

• The vertebral body is large, tall, and when viewed from superior, the vertebral body has a longer transverse diameter and a shorter anteroposterior diameter. Most anatomists describe the vertebral body as being “kidney-shaped”. The massiveness of the vertebral body is due to the larger weight that each consecutive vertebra has to bear in the lumbar region. Because of this, lumbar vertebrae have larger anular epiphyses, and the vertebral body is hourglass-shaped with a “waist”.  As with other vertebrae, the body of a lumbar vertebra has vertebral endplates, nutritional foramina, and in its posterior aspect they present with basivertebral foramina.

• The pedicles in the lumbar vertebrae are larger, course in a mostly anteroposterior direction, and have a oval cross-section where the superoinferior diameter is longer and the transverse diameter is shorter. This is important for transpedicular procedures for vertebroplasty or kyphoplasty.

Lumbar vertebra - inferior view
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• The transverse processes are also larger than other vertebrae. Of interest are the facts that the transverse process of the third lumbar vertebra is the longest of all lumbar vertebrae and that the transverse process of the fifth lumbar vertebra courses superolaterally at an angle of  almost 45 degrees because of the presence of the strong iliolumbar ligament. The lumbar transverse processes have a small tubercle called the mammillary process.

• The lumbar spinous processes are large and have a square shape.

Again, because of the larger weight bearing capacity of the lumbar vertebrae, they have strong ligaments and their zygapophyseal joints and articular facets tend to be oriented with their surfaces in a transverse plane. This has two consequences: The rotational mobility of the whole lumbovertebral region is limited and they tend not to have anteroposterior displacement.

Image property of CAA.Inc. Photographer: D.M. Klein.