Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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The Ephraim McDowell House and Museum (1)

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

In 2013 I wrote a short biography of Dr. Ephraim McDowell (1771- 1830) for the sidebar on this blog entitled “A Moment in History”. While researching the life of this illustrious surgeon I learned that his house is now a National Historic Landmark and has been transformed into a museum in the city of Danville, Kentucky. It took me almost four years but on Sunday February 19, 2017 I was able to go visit this place. Following is a series of articles and pictures of this visit.

The house itself was built in the 1790’s and most of it has been restored and lovingly maintained by the city, the Kentucky Medical Association, a Board of Directors, and a group of volunteers that work as docents giving tours of the house.

Ephraim McDowell House and MuseumThe Ephraim McDowell House and Museum

Visiting the Ephraim McDowell House and Museum Dr. Miranda in front of the Ephraim McDowell House

The following is an edited excerpt of Wikipedia on the McDowell House:

“After McDowell's death in 1830 the house was sold. It was the home of a Centre College president for a short time. Later the entire area became a slum and tenement property. The house deteriorated badly. Dr. August Schachner, of Louisville, led the efforts to buy the house for restoration. In 1921 he visited the house. "Since our last visit, the house has continued its downward course until it has reached a point where it now seems almost beyond redemption”. The room in the rear of the corresponding front room on the second floor,"(the operating room) "which is on a lower level by several feet, is used as a dump for the ashes from the grates of the rooms on the second floor."

The Kentucky Medical Association bought the house in 1935 and deeded it to the state of Kentucky, who had it restored by the Works Progress Administration (WPA). It was dedicated on May 20, 1939. In 1948, Kentucky returned the property to the Kentucky Medical Association.

The Kentucky Pharmaceutical Society restored the Apothecary Shop in the late 1950s with help from the Eli Lily Foundation. It was furnished by the Pfizer Laboratories. It was dedicated and presented to the Kentucky Medical Association on August 14, 1959.”

The house is located at 125 South Second Street, Danville, KY 40422. It is a white two-story wooden structure considered to be large for the time. To the right side stands a small one-story brick structure, the apothecary, where Dr. McDowell would provide medicine for his patients and others. To the left is the patio and garden where Dr. McDowell would grow medicinal plants for the apothecary. On the garden front there is a large two-sided plaque that reads:

Front of the plaque at the Ephraim McDowell House
Front of the plaque at the Ephraim McDowell House

“Home of Ephraim McDowell, the “father of modern surgery.” Here on December 25, 1809 McDowell performed the first successful abdominal operation when he took a 22-pound ovarian cysts from Jane Todd Crawford of Green Co. With no anesthesia, she sang hymns during the operation. Crawford recovered in 25 days and lived until 1842”

Back of the plaque at the Ephraim McDowell House and Museum
Back of the plaque at the Ephraim McDowell House

“Built in three stages. Brick ell, or single-story wing, built 1790s. McDowell purchased house in 1802 and added front clapboard section c.1804. Rear brick office and formal gardens added in 1820. House sold when McDowell dies in 1830. 1n 1930s, Ky. Med. Assoc. bought house; restored by WPA. House dedicated on May 20, 1939. Now a house museum”

This article continues here