Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


 "Clinical Anatomy Associates, Inc., and the contributors of "Medical Terminology Daily" wish to thank all individuals who donate their bodies and tissues for the advancement of education and research”.

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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Susan C. Potter
Susan C. Potter
Image capture from a video

The title of this article is a reference to another article in this blog: “The unknown patient / donor” which honors all those who have anonymously donated their bodies to further the anatomical training of many in the medical field. They trusted that those who would use their bodies would do so ethically and with respect, but they did not know exactly how they were to be used or what was going to be done with their bodies.

Susan Potter was the exact opposite. She knew that her body was going to be coated with polyvinyl alcohol, frozen, cut into four pieces with a huge handsaw, and then it would be ground or milled into 27,000 slices of 63 microns each, which were to be photographed in exquisite detail.

She offered her body to science and spoke with Dr. Vic Spitzer, who had directed the Visible Human Project, the first digital cadaver in 1994. She agreed to the donation, but only after she had toured the facilities and only after she clearly understood what was going to her body and why.

The why is the most interesting part of her story. Susan had a very interesting medical history, including spinal surgery , double mastectomy, and a hip replacement. Normally her body would have been rejected, but doctors see this type of patients in their practices. Patients who are old, frail, with prior surgeries and a multitude of problems. This is why she was chosen

If images are needed, usually cadavers are scanned and imaged postmortem, but in her case, Susan underwent many imaging studies while she was alive. She was interviewed and filmed countless times so that her videos would be added to the digital cadaver that was going to be made of her, becoming de facto, a digital patient.

Susan donated her body in the year 2000 died of pneumonia in 2015. During those 15 years she became a friend of Dr. Spitzer, gave talks to medical students, and collaborated with this project.

National Geographic followed Susan for these 15 years and documented her life and death. You can read her story here or watch the video in this article. The  development of the software continues. I am sure we will hear more from Susan Potter's contributions long after her death.

NOTE: My thanks to our contributor Pascalle Pollier for bringing Susan Potter to my attention. Dr. Miranda

“Clinical Anatomy Associates, Inc., and the contributors of "Medical Terminology Daily" wish to thank all individuals who donate their bodies and tissues for the advancement of education and research”.