Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Jean George Bachman

Jean George Bachmann
(1877 – 1959)

French physician–physiologist whose experimental work in the early twentieth century provided the first clear functional description of a preferential interatrial conduction pathway. This structure, eponymically named “Bachmann’s bundle”, plays a central role in normal atrial activation and in the pathophysiology of interatrial block and atrial arrhythmias.

As a young man, Bachmann served as a merchant sailor, crossing the Atlantic multiple times. He emigrated to the United States in 1902 and earned his medical degree at the top of his class from Jefferson Medical College in Philadelphia in 1907. He stayed at this Medical College as a demonstrator and physiologist. In 1910, he joined Emory University in Atlanta. Between 1917 -1918 he served as a medical officer in the US Army. He retired from Emory in 1947 and continued his private medical practice until his death in 1959.

On the personal side, Bachmann was a man of many talents: a polyglot, he was fluent in German, French, Spanish and English. He was a chef in his own right and occasionally worked as a chef in international hotels. In fact, he paid his tuition at Jefferson Medical College, working both as a chef and as a language tutor.

The intrinsic cardiac conduction system was a major focus of cardiovascular research in the late nineteenth and early twentieth centuries. The atrioventricular (AV) node was discovered and described by Sunao Tawara and Karl Albert Aschoff in 1906, and the sinoatrial node by Arthur Keith and Martin Flack in 1907.

While the connections that distribute the electrical impulse from the AV node to the ventricles were known through the works of Wilhelm His Jr, in 1893 and Jan Evangelista Purkinje in 1839, the mechanism by which electrical impulses spread between the atria remained uncertain.

In 1916 Bachmann published a paper titled “The Inter-Auricular Time Interval” in the American Journal of Physiology. Bachmann measured activation times between the right and left atria and demonstrated that interruption of a distinct anterior interatrial muscular band resulted in delayed left atrial activation. He concluded that this band constituted the principal route for rapid interatrial conduction.

Subsequent anatomical and electrophysiological studies confirmed the importance of the structure described by Bachmann, which came to bear his name. Bachmann’s bundle is now recognized as a key determinant of atrial activation patterns, and its dysfunction is associated with interatrial block, atrial fibrillation, and abnormal P-wave morphology. His work remains foundational in both basic cardiac anatomy and clinical electrophysiology.

Sources and references
1. Bachmann G. “The inter-auricular time interval”. Am J Physiol. 1916;41:309–320.
2. Hurst JW. “Profiles in Cardiology: Jean George Bachmann (1877–1959)”. Clin Cardiol. 1987;10:185–187.
3. Lemery R, Guiraudon G, Veinot JP. “Anatomic description of Bachmann’s bundle and its relation to the atrial septum”. Am J Cardiol. 2003;91:148–152.
4. "Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje" Icilio Cavero and Henry Holzgrefe Advances in Physiology Education 2022 46:4, 549-579.
5. Knol WG, de Vos CB, Crijns HJGM, et al. “The Bachmann bundle and interatrial conduction” Heart Rhythm. 2019;16:127–133.
6. “Iatrogenic biatrial flutter. The role of the Bachmann’s bundle” Constán E.; García F., Linde, A.. Complejo Hospitalario de Jaén, Jaén. Spain
7. Keith A, Flack M. The form and nature of the muscular connections between the primary divisions of the vertebrate heart. J Anat Physiol 41: 172–189, 1907.


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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Johannes Veslingius Mindanus
Click for the title page

Johannes Veslingius Mindanus (1598 – 1649). German surgeon, anatomist, botanist, and pharmacologist. Johann Vesling (mostly known by his Latinized name “Johannes Veslingius”) was born in a catholic family in Minden, Westphalia. He studied medicine in Leyden and Bologna. He later moved to the Venice medical college, where he became a professor of Anatomy in 1627. Veslingius had an interest in botany, which he pursued his whole life. Although German-born, Veslingius did most of his work and career in Italy. 

In 1628 he traveled to Egypt and Jerusalem as a personal physician of Alvise Cornaro, the Venetian consul in Cairo. In 1632 he became a professor of anatomy and surgery at the University of Padua, in Italy, forcing his return from Jerusalem. At Padua, Veslingius became part of the long list of anatomists that followed Andreas Vesalius’ position.

Veslingius was the first to describe the arterial circle of the brain, eponymically tied today to Thomas Willis, and he was the first to name the soleus muscle, as it resembles the sole fish. In his words: “soleus, a figura piscis denominatus” translated “soleus, named for its fish shape”. Apparently, he was also the first to describe the pancreatic duct which lead to controversy with Wirsung. Veslingius was also the first to describe the four pulmonary veins, described as four of the great vessels.

Veslingius published his most important work, “Syntagma Anatomicum, publicis dissectionibus in auditorum usum diligenter aptatum”, in 1641. This work, which originally had no images, was republished in 1647 with full images in copper plates. This original work is important as it leaves the Vesalian tradition of posing the anatomical images with backgrounds and landscapes, dedicating the image solely to the anatomical information; in fact this is the first book to publish original images not copied or inspired from Vesalius’ Fabrica.  This book was the first to influence Japanese anatomy.

Incredibly, Veslingius was accused of murdering Johan Georg Wirsung (1589 - 1643) with whom he had academic conflicts. Veslingius was acquitted of the accusation, and the name of Wirsung is today eponymously attached to the pancreatic duct.

The accompanying image is from the “Syntagma Anatomicum” and shows Veslingius with the following Latin words around him: “Ioannes Veslingius Mindanus Eques Hieros In Patauino Gymnasio Anatom. et Phar. Profess. Primarius” translated as: Johannes Veslingius Mindanus, Knight of Jerusalem, Primary Professor of Anatomy and Pharmacology of the School of Padua.

Below the image you can read: “Talis Apollinea floret Veslingius Arte. Purpureus nives pectore fulget Honor”, translated as:  Veslingius flourishes by the art of Apollo who honors him by shining purple snow on his chest. Click on the image for a larger depiction and to see the Latin text.

Personal note: I am proud to have in my library catalog one of Veslingius’ original prints: “Tavole Anatomiche del Veslingio – Spiegate in Lingua Italiana” (Anatomical images from Veslingius, written in Italian), published in 1745 by Giovanni Battista Conzatti. Dr. Miranda

Original image  courtesy of NLM. The title page of Syntagma Anatomicum courtesy of archive.org. Both images are in the public domain. 

Sources:
1. “The Fabric of the Body. European Tradition of Anatomical Illustration” Roberts KB, Tomlinson JDW (1992) Oxford: Clarendon.
2. “The evolution of anatomical illustration and wax modelling in Italy from the 16th to early 19th centuries” Riva, A. et al. J. Anat. (2010) 216, 209–222
3. “The Anatomical School of Padua” Porzionato, A. et al. Anat Rec (Hoboken). 2012 Jun; 295(6):902-16
4. “The Origin of Medical Terms” Skinner, HA. 1970 
5. "Johann Vesling (1598–1649):Seventeenth Century Anatomist of Padua and His Syntagma Anatomicum" SK Ghosh J Clin Anat 2014 
Original image  courtesy of the National Library of Medicine. The title page of Syntagma Anatomicum courtesy of archive.org. Both images are in the public domain.