Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Johannes Veslingius Mindanus
Click for the title page

Johannes Veslingius Mindanus (1598 – 1649). German surgeon, anatomist, botanist, and pharmacologist. Johann Vesling (mostly known by his Latinized name “Johannes Veslingius”) was born in a catholic family in Minden, Westphalia. He studied medicine in Leyden and Bologna. He later moved to the Venice medical college, where he became a professor of Anatomy in 1627. Veslingius had an interest in botany, which he pursued his whole life. Although German-born, Veslingius did most of his work and career in Italy. 

In 1628 he traveled to Egypt and Jerusalem as a personal physician of Alvise Cornaro, the Venetian consul in Cairo. In 1632 he became a professor of anatomy and surgery at the University of Padua, in Italy, forcing his return from Jerusalem. At Padua, Veslingius became part of the long list of anatomists that followed Andreas Vesalius’ position.

Veslingius was the first to describe the arterial circle of the brain, eponymically tied today to Thomas Willis, and he was the first to name the soleus muscle, as it resembles the sole fish. In his words: “soleus, a figura piscis denominatus” translated “soleus, named for its fish shape”. Apparently, he was also the first to describe the pancreatic duct which lead to controversy with Wirsung. Veslingius was also the first to describe the four pulmonary veins, described as four of the great vessels.

Veslingius published his most important work, “Syntagma Anatomicum, publicis dissectionibus in auditorum usum diligenter aptatum”, in 1641. This work, which originally had no images, was republished in 1647 with full images in copper plates. This original work is important as it leaves the Vesalian tradition of posing the anatomical images with backgrounds and landscapes, dedicating the image solely to the anatomical information; in fact this is the first book to publish original images not copied or inspired from Vesalius’ Fabrica.  This book was the first to influence Japanese anatomy.

Incredibly, Veslingius was accused of murdering Johan Georg Wirsung (1589 - 1643) with whom he had academic conflicts. Veslingius was acquitted of the accusation, and the name of Wirsung is today eponymously attached to the pancreatic duct.

The accompanying image is from the “Syntagma Anatomicum” and shows Veslingius with the following Latin words around him: “Ioannes Veslingius Mindanus Eques Hieros In Patauino Gymnasio Anatom. et Phar. Profess. Primarius” translated as: Johannes Veslingius Mindanus, Knight of Jerusalem, Primary Professor of Anatomy and Pharmacology of the School of Padua.

Below the image you can read: “Talis Apollinea floret Veslingius Arte. Purpureus nives pectore fulget Honor”, translated as:  Veslingius flourishes by the art of Apollo who honors him by shining purple snow on his chest. Click on the image for a larger depiction and to see the Latin text.

Personal note: I am proud to have in my library catalog one of Veslingius’ original prints: “Tavole Anatomiche del Veslingio – Spiegate in Lingua Italiana” (Anatomical images from Veslingius, written in Italian), published in 1745 by Giovanni Battista Conzatti. Dr. Miranda

Original image  courtesy of NLM. The title page of Syntagma Anatomicum courtesy of archive.org. Both images are in the public domain. 

Sources:
1. “The Fabric of the Body. European Tradition of Anatomical Illustration” Roberts KB, Tomlinson JDW (1992) Oxford: Clarendon.
2. “The evolution of anatomical illustration and wax modelling in Italy from the 16th to early 19th centuries” Riva, A. et al. J. Anat. (2010) 216, 209–222
3. “The Anatomical School of Padua” Porzionato, A. et al. Anat Rec (Hoboken). 2012 Jun; 295(6):902-16
4. “The Origin of Medical Terms” Skinner, HA. 1970 
5. "Johann Vesling (1598–1649):Seventeenth Century Anatomist of Padua and His Syntagma Anatomicum" SK Ghosh J Clin Anat 2014 
Original image  courtesy of the National Library of Medicine. The title page of Syntagma Anatomicum courtesy of archive.org. Both images are in the public domain.