Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Triangle of Calot

Triangle of Calot 
Image modified from the original
(Singh and Ohri, 2006

The [triangle of Calot], also known as the “cystohepatic triangle” is a triangular region found within the lesser omentum connecting the duodenum, stomach, and liver. It is an area bound superiorly by the inferior surface of the liver, laterally by the cystic duct and the medial border of the gallbladder, and medially by the common hepatic duct.

The surgical importance of this area is for a cholecystectomy. It is within this area that the surgeon will usually find the cystic artery, a critical structure that needs to be ligated in this procedure.  I stress the term “usually” as the hepatobiliary tree is one of the areas in the human body that has the most anatomical variations. In fact, the anatomy in this region is considered to be “normal” only in 64% of the cases. The cystic artery may not be found in the triangle of Calot therefore careful dissection and identification of the structures is needed in every surgery.

The above description of the triangle of Calot is what some refer to as the “modern triangle of Calot”, as the original triangle described by Dr. Jean-Francois Calot (1861 – 1944) is different.

Calot’s original description of this triangle is: “Le triangle n’est pas exactement équilatéral, mais plutôt isocéle, les deux cotés supérieur et inférieur, représente par l’artére et le conduit cystique, étant seuls égaux, et un peu plus longs que la partie du canal hépatique qui entre dans la constitution du triangle’’ , which can be translated as: “ The triangle is not exactly equilateral, but rather an isosceles triangle. The superior and inferior sides, represented by the cystic artery and cystic duct, are equal and a little longer than the part of the hepatic duct, which enters into the formation of the triangle. (Abdalla, 2013).

In the accompanying image Calot’s original triangle is shown by horizontal blue lines while the modern version of the triangle of Calot is shown with vertical red lines.

Sources:
1. “Calot's triangle” Abdalla S, Pierre S, Ellis H. Clin Anat. 2013 May;26 (4):493-501
2. “Anatomic landmarks: their usefulness in safe laparoscopic cholecystectomy” Singh, K; Ohri, A. Surg Endosc (2006) 20: 1754–1758
3. “Surgical Anatomy” Deaver, J P. Blakiston's Son & Co. Philadelphia, 1901
4. "Tratado de Anatomia Humana" Testut et Latarjet 8th Ed. 1931 Salvat Editores, Spain
Image modified from the original (Singh and Ohri, 2006. Pastel sketch by Dr. E. Miranda