Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Jean George Bachman

Jean George Bachmann
(1877 – 1959)

French physician–physiologist whose experimental work in the early twentieth century provided the first clear functional description of a preferential interatrial conduction pathway. This structure, eponymically named “Bachmann’s bundle”, plays a central role in normal atrial activation and in the pathophysiology of interatrial block and atrial arrhythmias.

As a young man, Bachmann served as a merchant sailor, crossing the Atlantic multiple times. He emigrated to the United States in 1902 and earned his medical degree at the top of his class from Jefferson Medical College in Philadelphia in 1907. He stayed at this Medical College as a demonstrator and physiologist. In 1910, he joined Emory University in Atlanta. Between 1917 -1918 he served as a medical officer in the US Army. He retired from Emory in 1947 and continued his private medical practice until his death in 1959.

On the personal side, Bachmann was a man of many talents: a polyglot, he was fluent in German, French, Spanish and English. He was a chef in his own right and occasionally worked as a chef in international hotels. In fact, he paid his tuition at Jefferson Medical College, working both as a chef and as a language tutor.

The intrinsic cardiac conduction system was a major focus of cardiovascular research in the late nineteenth and early twentieth centuries. The atrioventricular (AV) node was discovered and described by Sunao Tawara and Karl Albert Aschoff in 1906, and the sinoatrial node by Arthur Keith and Martin Flack in 1907.

While the connections that distribute the electrical impulse from the AV node to the ventricles were known through the works of Wilhelm His Jr, in 1893 and Jan Evangelista Purkinje in 1839, the mechanism by which electrical impulses spread between the atria remained uncertain.

In 1916 Bachmann published a paper titled “The Inter-Auricular Time Interval” in the American Journal of Physiology. Bachmann measured activation times between the right and left atria and demonstrated that interruption of a distinct anterior interatrial muscular band resulted in delayed left atrial activation. He concluded that this band constituted the principal route for rapid interatrial conduction.

Subsequent anatomical and electrophysiological studies confirmed the importance of the structure described by Bachmann, which came to bear his name. Bachmann’s bundle is now recognized as a key determinant of atrial activation patterns, and its dysfunction is associated with interatrial block, atrial fibrillation, and abnormal P-wave morphology. His work remains foundational in both basic cardiac anatomy and clinical electrophysiology.

Sources and references
1. Bachmann G. “The inter-auricular time interval”. Am J Physiol. 1916;41:309–320.
2. Hurst JW. “Profiles in Cardiology: Jean George Bachmann (1877–1959)”. Clin Cardiol. 1987;10:185–187.
3. Lemery R, Guiraudon G, Veinot JP. “Anatomic description of Bachmann’s bundle and its relation to the atrial septum”. Am J Cardiol. 2003;91:148–152.
4. "Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje" Icilio Cavero and Henry Holzgrefe Advances in Physiology Education 2022 46:4, 549-579.
5. Knol WG, de Vos CB, Crijns HJGM, et al. “The Bachmann bundle and interatrial conduction” Heart Rhythm. 2019;16:127–133.
6. “Iatrogenic biatrial flutter. The role of the Bachmann’s bundle” Constán E.; García F., Linde, A.. Complejo Hospitalario de Jaén, Jaén. Spain
7. Keith A, Flack M. The form and nature of the muscular connections between the primary divisions of the vertebrate heart. J Anat Physiol 41: 172–189, 1907.


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How many scientists, physicians, or anatomists have musical pieces written for them? I was so surprised when I found out that there is a musical score entitled “André Vésale” written by Louis-Jean Abadie and published in 1861 in Paris, France. I felt the obligation to research this topic.

There are many people that follow the life and works of Andreas Vesalius, a 16th century anatomist who started the modern scientific approach to human anatomy and medicine. I count myself in this group that includes artists, historians, poets, painters,musicians, medical illustrators, physicians, surgeons, antique collectors, anatomists, etc.

In June 2023, I had the honor of being invited by the University of Antwerp in Belgium to speak at the 2023 Vesalius Triennial Meeting. It was here that I discovered this musical surprise!

Theo Dirix
Elke Robersscheuten

Theo Dirix
Theo Dirix

One of the events of this meeting was an afternoon concert entitled “Vesalian landscapes in music, poetry, and photographs” by pianist Elke Robersscheuten, and my friend Theo Dirix, who read the poetry. This was accompanied by slides of Vesalian works, and images of the city of Brussels and the island of Zakynthos, Greece. One of the pieces performed by Elke Robersscheuten was “André Vésale”. You can see Elke perform this piece in a video at the end of this article.

With the help of Theo, I started the process of unraveling the story of this musical piece:

Abadie, Louis-Jean (c1814-1858). Public domain
Louis Abadie

The author

Abadie, Louis-Jean (c1814-1858). Louis Abadie was a baritone singer. He started performing in the French provinces as member of an opera troupe. In 1842 he settled in Paris where he wrote numerous chansons and romances which were very popular at the Paris salons at the time. He had success as singer and voice teacher in Paris and in 1848 he released records of his songs, which were well received. I have not been able to find copies of these records.

He went back to traveling and singing, with little success and decided to move to Bordeaux, and then back to Paris where he was unsuccessful trying to find a locale that would present his work to the public. He lived in poverty and in early December 1958 he had a stroke and died at 45 years old, leaving a wife and three children. As a side note to his life, many of his works were dedicated or mentioned by name a woman named Jeanne. His wife's name was Marie Jeanne Toussaint.

Seven years after his death, on May 2, 1867, Les Danseurs de Corde.(The Rope Dancers) , an operetta (comedic opera) in two acts for which he had written the music, was performed at the Théâtre des Folies-Saint-Germain.

The lyrics

The poignant lyrics to this work were written by Louis-Adolphe Turpin de Sansay (1832 – 1891) a prolific French dramatic author, chansonnier, and songwriter. He collaborated with musicians with lyrics for their work. The lyrics for “André Vésale” were written in 1860 and published the following year.

The works of Turpin de Sansay were presented in elite places line the Théâtre des Champs-Élysées, the Théâtre des Bouffes-Parisiens, the Théâtre Beaumarchais, and the Théâtre-Lyrique.

The lyrics for “André Vésale” are based on Vesalius being deported to the Greek island of Zakynthos (known then as Zanthe). We now know this is a legend and not true. Following is the French original and a free translation of this work:

"André Vésale" (French)

Dans un caveau sur ma table de pierre
J'ai de la mort compulsé les secrets.
J'ai de mes mains profané la matière,
Et maintenant j'éprouve des regrets.
Par mon travail si de l'anatomie
J'ai découvert et promulgué la loi:
Si j'ai cherché les sources de la vie,
Pardonnez-moi, mon Dieu, pardonnez-moi!

Ils m'ont banni sur la terre de Zante,
Ils m'ont traité d'impie et d'imposteur;
Et j'ai dû tendre une main suppliante,
Car sur mon front plane le noir malheur!
Mais l'avenir, qui devant moi rayonne,
A ranimé mon courage et ma foi;
Si j'ai rêvé du martyr la couronne,

Pardonnez-moi, mon Dieu, pardonnez-moi!
J'aurais voulu calmer chaque souffrance,
Venir en aide à notre humanité,
Malgré l'exil, cependant, la science
Se répandra dans la postérité!
A mon pays, quoi qu'ingrat, je signale
Mes longs travaux, c'est mon bien, c'est mon droit.
Si j'illustrai le nom d'André Vésale,
Pardonnez-moi, mon Dieu, pardonnez-moi!

"Andreas Vesalius" (English)

In a cellar, on my stone table
I have extracted the secrets of death.
I have desecrated matter with my hands,
And now I feel regret.
By my work of anatomy
I discovered and promulgated the law:
If I sought the sources of life,
Forgive me, my God, forgive me!

They banished me to the land of Zakynthos,
They called me impious and impostor.
And I had to hold out a pleading hand,
For on my forehead hovers black misfortune!
But the future, which shines before me,
Revived my courage and my faith.
If I dreamed of the martyr's crown,
Forgive me, my God, forgive me!

I would have liked to calm each suffering,
Come to the aid of humanity,
Despite the exile, however, science
Will spread to posterity!
To my country, although ungrateful, I point out (that)
My vast work is my property, it is my right.
If I inscribe the name of Andreas Vesalius,
Forgive me, my God, forgive me!

The publisher

Étienne Challiot (1837 – 1866) had his office located at 352-354 Rue St Honoré, in Paris, very close to Place Vendôme, Paris. He published books and music sheets. Some of his publications can be found online.

The printer

Almost nothing is known about the printer of this work. A female printmaker, Madame Dinquel, had her printer shop at 276 Rue Sain Honoré, in Paris, very close to the publisher Étienne Challiot. Today, Sapporo, a Japanese restaurant sits at this address.

The musical piece

 Following is a video of pianist Elke Robersscheuten performing "André Vésale" by Luis Abadie.


The original score can be downloaded here. Thanks to IMLSP for preserving this music for posterity. You can click on the image for a larger depiction.

André Vésale sheet music by Luis Abadie. Public Domain
André Vésale sheet music by Luis Abadie. Public Domain

Sources:
1. Biographie universelle des musiciens et bibliographie générale de la musique, Volume 1François-Joseph Fétis Libraire de Firmin-Didot, 1878 Paris
2. Obituary: Courrier de la librairie: journal de la propriété littéraire et artistique pour la France et pour l'étranger. 1858,7/12
3. Necrologie; B. JOUVIN. Théatres (French). Paris: Figaro, 09/12/1858. Article nécrologique dans Le Figaro (Lire en ligne sur Gallica)
4. Obituary: Courrier de la librairie: journal de la propriété littéraire et artistique pour la France et pour l'étranger. 1858,7/12
5. Frédéric Caille, La figure du sauveteur : Naissance du citoyen secoureur en France, 1780-1914, Presses Universitaires de Rennes, 2006, p. 222-224 6.