Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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In the shadow of Vesalius cover
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This is a new, as yet unpublished, book authored by several of my good friends who with me follow Vesaliana all over the world. There are too many of my friends to count, but I highly recommend this book. Dr. Miranda

In this richly illustrated book, a multitude of academic scholars present new findings concerning Andreas Vesalius Bruxellensis  and his contemporaries. One of those discoveries includes a preparatory sketch by Jan Steven van Calcar for a drawing in Vesalius’ famous ‘Fabrica’, called ‘The Philosopher’.

Included are authentic letters, written by Vesalius to his friends Benedetto Varchi and Octavo Landi, are presented and translated for the first time and are thoroughly discussed, shedding new light on crucial periods of Vesalius’ life like his leave from academic Padua, exchanged  for imperial service to Charles V, or his contribution in the treatment of Philips II’s son, crown prince Carlos in Spain.

Anatomical novelties, discovered by Vesalius’ friends and contemporaries, are equally broadly exposed, like Canani’s input in human arm musculature or Valverde’s ‘corrections’ of Vesalius’ Epitome. Valverde’s publication became one of the greatest ‘bestsellers’ in anatomy during the 16th and 17th century, thereby spreading the ‘Vesalian Revolution’ all over Europe.  But also, the relationship between Vesalius and his Paduan room mate John Kay or Caius is explicated, as are a number of family descendants of Vesalius.

That Vesalius influenced artists in anatomical models and drawings is newly acknowledged in this book, as well as his influence on veterinary medicine.

In short, an inspiring new account of Vesalius’ extraordinary long-term influence on anatomy, science and art in general. One interesting point is that until now, many of the series of articles that composes the book where only available in Greek!

Jacqueline Vons (Emer. Professor of Latin and Medical History, University of Tours, France) comments "Centered around the figure of Andreas Vesalius (1514-1564), this book ‘In the Shadow of Vesalius’ offers a vast panorama of the anatomical knowledge in Europe during early Modern times.

Pascale Pollier
Pascale Pollier-Green

Some new documents and private letters have been discovered and are finely analyzed, as are anatomical books written by contemporaries and successors of Vesalius. The studies gathered here show how the text and iconography’s diffusion of De Humani Corporis Fabrica and Epitome made Vesalius the first modern medical authority (auctoritas): his work was quoted, copied, discussed by all those who were interested in the anatomy of the human body."

Click here to download a PDF file with a description of the book, the Table of Contents, and the information to pre-order this book which will be launched on November 14, 2020. To order a book at a pre-launch discounted price, you can go directly to the publisher's website (http://garant.be/shadow-of-vesalius/).

Pascale recently wrote an article looking back at how this book came to be. Here is the story of "The Long Road to the book "In the Shadow of Vesalius"