Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Pavlos Plessas

Pavlos Plessas
Pavlos Plessas


Pavlos Plessas
was born and brought up on the island of Zakynthos (Zante) in Greece. He lives in London but maintains an internet blog that explores the history of his native island. He is a historian of the island and an internet blogger.

Knowing the island, its history and its people he never believed that Vesalius was shipwrecked, left to die helpless and buried near the beach of Laganas. When the local interest in Vesalius was rekindled by the visit of Pascale Pollier and Theo Dirix, he tried to separate the evidence from rumours and speculation to see if a rational explanation of the mystery could be found.

He was approached by Pascale Pollier and Theo Dirix and asked to assist in their search for Vesalius' grave. With the help of local people and old maps he found the approximate location of the Santa Maria church, by which Vesalius had been buried. The scientific work of Dr. Sylviane Dederix confirmed that this was indeed the spot where the church once stood.

Thanks to Pavlos Plessas for collaborating with "Medical Terminology Daily" and allowing us to re-publish his work on "Powerful indications that Vesalius died from scurvy", presented originally at the 2014 "Vesalius Continuum" meeting in Zakynthos, Greece.


UPDATE: Pavlos' article and theory was refutted by Theo Dirix and Dr. Rudi Coninx. both contributors to this blog. Their article is entitled "Did Andreas Vesalius really die from Scurvy?". Not to be undone, Pavlos published his own rebuttal to their theory in the article "An answer regarding the death of Andreas Vesalius".


Following are some links to Pavlos Plessas' blog articles: