Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Esophageal hiatus hernia

Esophageal hiatus hernia in situ.The arrow points to stomach and greater omentum herniating into the thorax
Esophageal hiatus hernia in situ.
The arrow points to stomach and greater
omentum herniating into the thorax

UPDATED: An esophageal hiatus hernia (also known as a hiatal hernia) is caused by a dilation of the esophageal hiatus and its component structures, the phrenoesophageal membranes (ligaments).

Since the intraabdominal pressure is higher than the intrathoracic pressure, abdominal contents -usually stomach and greater omentum- can herniate through the dilated esophageal hiatus into the mediastinum, the central region of the thoracic cavity. This presents as a hernia sac whose walls are formed by endothoracic fascia, phrenoesophageal membranes and parietal peritoneum. 

There are two main types of esophageal hiatus hernias. Type I is known as a "sliding hiatal hernia" and is characterized by a complete ascension of the esophagogastric junction and abdominal esophagus into the thoracic hernia sac. This is usually accompanied by a typical "hourglass image" in a radiographic assessment, and also presents with gastroesophageal reflux disease (GERD). Type I esophageal hiatus hernias are more common.

Esophageal hiatus hernia, reduced. The dotted line shows the edge of the enlarged esophageal hiatus
Esophageal hiatus hernia, reduced.
The dotted line shows the edge of
the enlarged esophageal hiatus

Type II esophageal hiatus hernia is known as a "paraesophageal hernia" and represent about 5 - 15% of esophageal hiatus hernias. In this case, the esophagogastric junction maintains its anatomical position inferior to the respiratory diaphragm, but the fundus and body of the stomach, along with some greater omentum herniate alongside the esophagus into the mediastinal region of the thoracic cavity. Although there can be GERD, this type of hernia usually presents with little symptomatology, and when it does, symptoms are related to ischemia or partial to complete obstruction. There are variations of type II hernia, which are classified as Type III and IV. Type IV, although rare, will include other viscera in the hernia sac, including colon, spleen, or even small intestine.

The accompanying images above depict a Type I esophageal hiatus hernia. The superior image shows the hernia in situ where the stomach and greater omentum are still in the hernia sac. The inferior image shows the contents reduced and the abdominal esophagus being pulled into the abdominal cavity. The dotted line shows the dilated esophageal hiatus that needs to be repaired to prevent recurrence of the pathology.

Click on this link for additional information on esophageal hiatus hernia surgery.

The image below answers a question by Victoria Guy Ratcliffe, who asked via Facebook "What would it be if it feels like you've got a blockage right at the level of the heart? That's too high for a hiatal hernia, isn't it?" The image answers the question. It shows a dissection of the left side of the thorax. The anterior thoracic wall and the left lung have been removed. The heart is immediately superior and anterior to the esophageal hiatus, and the hernia sac of a Type I esophageal hiatus hernia is seen immediately posterior and in contact with the heart. Whether this means that you will "feel" the hernia, it is up for debate, as all these structures have visceral innervation. Most probably, a well-developed Type II esophageal hiatus hernia might interfere with swallowing at this level, causing the sensation she mentions. Thanks for the question, Tori.

Type I esophageal hiatus hernia<em>.</em>The hernia sac can be seen posterior to the heart

For additional information:
"Approaches to the Diagnosis and Grading of Hiatal Hernia" Kahrilas et al Best Pract Res Clin Gastroenterol. 2008 ; 22(4): 601–616.