Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Mesentery

Dissection of the abdomen. The greater omentum is being pulled anteriorly
Click for a larger image

UPDATED: The term [mesentery] is of Greek origin. The prefix [mes(o)-] arises from the Greek [μέσο] meaning "middle", the root term [-enter-] means "small intestine" or "intestine", and the suffix [-y] means "process" or "structure". Thus, the mesentery is "a structure in the middle".

The term [mesentery] can be used as a generic word to denote a double-layered peritoneal membrane that stretches between an abdominal viscus and the abdominal wall. A more precise use of the term is that of mesentery proper, which extends between the posterior abdominal wall and the jejunum and ileum. The superior mesenteric artery and veins are found at the root of the mesentery proper, along with a large accumulation of lymphatic nodes, and sympathetic and parasympathetic nerves.

Between the two layers of the mesentery proper, there are jejunal and ileal arteries and veins, a complex system of arterial and venous arches, as well as lymphatic vessels,  autonomic nerves, and varying degrees of fat. Because of the presence of the mesentery proper, the jejunum and ileum are mobile or intraperitoneal, that is, they can slither, turn and twist with the movements of peristalsis. This movement is helped by the presence of a small amount of peritoneal fluid.

Transillumination of the transverse mesocolon. Courtesy of Michiaki Akashi, MD
Click for a larger image

The fact that the mesentery is intraperitoneal is important in surgery. If the organ can already move around because of its mesentery, then it does not need to be "mobilized", it is already mobile!! If the organ (jejunum or ileum) have adhesions that limit their mobility within the abdominal cavity, the surgeon may have to perform and adhesiolysis to restore their mobility.

The first image shows an anatomical dissection where the greater omentum has been pulled anteriorly, exposing the small intestine and its mesentery, as well as the transverse mesocolon. Click on the image for a larger depiction. The second image (courtesy of Dr. Michiaki Akashi) is artwork depicting the surgical technique of transillumination, where the surgeon will shine a light through the mesentery to visualize the blood supply to the intestine prior to ligation and transection. The mesentery-like structure being transilluminated is the transverse mesocolon

WARNING: The first image is a photograph of a human dissection and can be considered descriptive.

NOTE: My personal thanks to Michiaki Akashi, M.D.for allowing us to use his artwork in this article. Dr. Akashi works as a surgeon and pathologist in the Saga Prefectural Hospital Koseikan in Saga, Japan.Dr. Miranda

First image property of: CAA.Inc. Photographer: David M. Klein