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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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The anterior cerebral arteries are one of the two paired terminal branches of the internal carotid artery. Each anterior cerebral artery supplies arterial blood to the brain beyond the arterial circle of Willis. The vascular territory of the anterior cerebral artery supplies the medial surfaces of the frontal and parietal cerebral lobes as well as the medial border of the same lobes.
The anterior cerebral artery gives off the orbitofrontal artery and then divides into two callosal arteries, the pericallosal artery and the callosomarginal artery. From these arteries arise all the other branches that form the vascular territory of the anterior cerebral artery.
There are many anatomical variations of the anterior cerebral artery, as described here.
Clinical anatomy, pathology, and surgery of the brain and spinal cord are some of the lecture topics developed and delivered by Clinical Anatomy Associates, Inc.
Image modified from the original (in the public domain) by Sobotta (1945)
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The medical term thrombus arises from the Greek [θρόμβος] (pronounced thrombos) meaning "a lump", "a piece of milk curd", or a "clot". This Greek term was later adopted in Latin [thrombus] and is used in this unchanged form today. The plural for thrombus is [thrombi]. A synonymous Latin term is [coagulum] (pl. coagula).
In medicine, a thrombus is a blood clot that has the connotation of being stationary, fixed to a vessel wall. If this blood clot were to be freed and start moving with the blood flow, then the clot should be called an "embolus" (Lat; pl. emboli).
Because of its anatomical characteristics. in the presence of atrial fibrillation, the left atrial appendage is particularly prone to the formation of thrombi, which can embolize and cause brain strokes.
The root term for this word is [-thromb-]. Examples of its use are:
- Thrombosis: The suffix [-osis] means "condition" with the connotation of "many". A condition of multiple thrombi
- Thrombocytopenia: A combination of root terms; the root term [-cyt-] means "cell" and the suffix [-(o)penia] means "a deficiency". A deficiency of platelets (the "clotting" cells)
Sources:
1. "The Origin of Medical Terms" Skinner, HA 1970 Hafner Publishing Co.
2. "Medical Meanings - A Glossary of Word Origins" Haubrich, WD. ACP Philadelphia
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Tracheobronchial tree
The trachea, vernacularly known as the "windpipe", is in the adult a 4 inch (10.1 cm) membranous tube which contains incomplete, almost circular rings of cartilage. Some authors describe between fourteen to sixteen of these incomplete rings of cartilage in the trachea.
These semicircular rings are open-ended posteriorly, where the trachea only has a membrane, thus being flattened posteriorly. This posterior aspect of the trachea is in close anatomical relationship with the thoracic esophagus.
The trachea begins at the inferior end of the larynx, just about the level of the sixth cervical vertebra, and descends in the superior mediastinum to the level of the sternal angle (of Louis) close to the superior border of the fifth thoracic vertebra, where it divides into two main bronchi, each entering the ipsilateral lung at the level of the pulmonary hilum.
The word [trachea] arises from the Greek [trakhus] meaning "rough". This is because in the original description of this structure there was the belief that all arteries were full of air (Lat. air = ar/aria). The trachea, being rough was called the "rough artery" or "tracheartery", which was later amended, eliminating the "artery" part. In Latin the term used for the trachea was [arteria aspera], also meaning "rough artery".
The internal lower border of the bifurcation of the trachea into the left and right main bronchi is knows as the carina, where the carinal lymphatic nodes are found.
Sources:
1 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Anatomy of the Human Body" Henry Gray 1918. Philadelphia: Lea & Febiger
Image modified by CAA, Inc. Original image courtesy of bartleby.com
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Posterior view of the contents of the thoracic cavity.
The descending aorta, also known as the thoracic aorta is the third portion of the aorta. It is found distal to the aortic arch in the posterior portion of the inferior mediastinum, and proximal to the abdominal aorta.
The descending aorta is situated between the lungs and has a close relation with the thoracic esophagus and the thoracic duct.
The descending aorta gives off 10 pairs of posterior intercostal arteries. The first intercostal artery, known as the supreme intercostal artery arises as a branch of the costocervical trunk of the subclavian artery. The last pair of arteries to arise from the descending aorta are the subcostal arteries, which pass under the 12th rib. The descending aorta also gives a number of smaller branches to the esophagus and the main stem bronchi.
The descending aorta ends at the aortic hiatus, where it continues as the abdominal aorta.
Sources:
1 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Anatomy of the Human Body" Henry Gray 1918. Philadelphia: Lea & Febiger
Image modified by CAA, Inc. Original image courtesy of bartleby.com
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First used by Galen of Pergamon (129AD - 200AD) the word [etiology] is of Greek origin. [αiτία] or [aitia], meaning "cause" or "reason", and [λογία] or [-ology], meaning "study of". Etiology is the "study of cause". In medicine this word is used to denote the study of the causes for a pathology, disease, or condition.
Because of its Greek origin, Skinner (1970) states that the proper way of spelling this term should be aetiology, but the initial "a" has been discarded through use.
There are many pathologies of unknown origin. In this case the word to use would be [idiopathic] or [idiopathy] meaning "of unknown cause"
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The suffix [-(o)cele] arises from the Greek [κήλη] meaning "dilation" or "pouching". In medical terminology this suffix is used to mean "hernia", "bulging", or a "dilation". In older times a synonym was used for hernia: "rupture".
Dr. Aaron Ruhalter would state the proper description for an "ocele" is that of a prolapse, that is, a herniation without a hernia sac.
Examples the use of [ocele] are:
- Orchiocele: The prefix [orchi-] means "testicle" or "scrotum". Refers to a scrotal or testicular bulging, a scrotal hernia
- Hydrocele: The root term [-hydr-] means "water". A watery dilation. Usually used to refer to the accumulation of fluids in the scrotum
- Hydatidocele: Refers to a dilated cyst containing hydatids, the larval form of the tapeworm Echinococcus granulosus or Echinococcus multilocularis
- Enterocele: The root term [-enter-] means "intestine" or "small intestine". The bulging of the small intestine into the vagina because of weakness of the vaginal wall
- Cystocele: The root term [-cyst-] means "bladder" or "sac". The bulging of the urinary bladder into the vaginal canal because of weakness of the vaginal wall
- Cystourethrocele: A combination of root terms; [-cyst-] means "bladder" or "sac" and [-urethr-] means "urethra". The bulging of the urinary bladder and urethra into the vaginal canal
- Myelomeningocele: A combination of root terms; [-myel-] means "spinal cord" (also "bone marrow") and [-mening-] means "menynx". The herniation of the spinal cords and its meningeal coverings into the back, creating a bulge
- Varicocele: The root term [-varic-] means "varix" or "sac". A bulging of the skin caused by varices