Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.
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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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Medical suffix originating from the old Greek [πλήσσειν] (plessein) meaning “to strike” or the modern Greek [πληγείσες] meaning “stricken”. Its meaning in modern medical terminology is “paralysis”, the loss or impairment of bodily movement. This suffix can be seen in many medical terms:
- Quadriplegia: From the term [quad] meaning “four”. Loss of movement or paralysis in all four extremities
- Hemiplegia: From the prefix [hemi-] meaning “half”. Loss of movement or paralysis in one half of the body
- Paraplegia: The prefix [para-] means “alongside” or “parallel to”. Originally the word paraplegia was synonymous with [hemiplegia], but in modern times it is used to denote loss of movement or paralysis in the lower half of the body
- Cardioplegia: The root term [card] means “heart”. Stopping or paralyzing the heart. This is done as part of a heart operation where a solution is placed into the heart to stop it and allow for heart surgery. In the case of minimally invasive surgery retrograde cardioplegia is used by placing the cardioplegia solution through a catheter into the coronary sinus.
Note: The links to Google Translate include an icon that will allow you to hear the Greek or Latin pronunciation of the word.
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The septum pellucidum is a thin, transparent membrane that forms the medial wall of the lateral ventricles.
The term [septum] means “wall” or “partition” and [pellucidum] means “transparent”.
The septum pellucidum is found most of the time as a single, median structure that is shared by both lateral ventricles and is sometimes perforated, which has no pathological consequence.
In some cases this structure can be double, creating a separate medial wall for each lateral ventricle. When this happens the space between the lateral ventricles has been named the “cavum septi pellucidi”, the “fifth ventricle”, or is eponymically called the “ventricle of Vieussens”. This is shown in the accompanying image
Image modified from the original from “Surgical Anatomy” by John Deaver 1901. Public domain.
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The lateral ventricles of the brain are two separate cavities, each found within a cerebral hemisphere. The lateral ventricles are part of the ventricular system of the brain and contain cerebrospinal fluid which is produced within the ventricular system in the choroid plexuses, most of which are found in the lateral ventricles.
Each lateral ventricle communicates with the third ventricle by way of an interventricular foramen, also known as the foramen of Monro, allowing for circulation of the cerebrospinal fluid
Each lateral ventricle has four components:
1. The central component or “body”. This area is found superior to the thalamus and inferior to the corpus callosum
2. An anterior extension called the “frontal horn”. The boundary between the body and the frontal horn is the interventricular foramen of Monro
3. A posterior extension called the “occipital horn”
4. An anteroinferior extension called the “temporal horn”
The body of the lateral ventricle and the occipital and temporal horn meet at a common point called the “ventricular crossroad” or “isthmus”.
The accompanying animated image shows the lateral ventricles in red. Click on the image for a larger depiction
Sources:
1 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 1995.
3. Image credits: By Images are generated by Life Science Databases (LSDB). (License information))], public domain, via Wikimedia Commons
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The medical prefix [hemi-] means “half”. It is also the basis for the prefix [semi-] , also meaning “half”. We can see this term used in many medical terms such as:
- Hemisphere: literally “half a sphere”, as in the case of the cerebral hemispheres
- Hemiplegic: Paralized only on one half of the body
- Hemialgia: Pain on one half (of the body)
- Hemicephalalgia: Pain on one half of the head, a migraine
- Semilunar: Half a moon, name used for the aortic and pulmonary valves
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The eponym “ring of Vieussens” refers to a collateral circulation anastomotic communication between the right conal artery and the left conal artery. This communication, when present, is a potential life-saving pathway when there is stenosis or obstruction at the origin of either the right or the left coronary arteries, allowing blood to bypass the blockage.
This anastomosis is sometimes evident, although sometimes when the anastomosis is not seen on the surface of the heart, there is the possibility that the anastomosis is present subepicardially as demonstrated in the 2014 study by Loukas et al.
This ring is demonstrated in the accompanying image. For a three-dimensional volume–rendered CT demonstrating Vieussens’ collateral pathway please click here. For the full 2006 article by Hansen, click here.
Image property of CAA, Inc. Artist: Victoria Ratcliffe.
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The conal artery is the first anterior branch that arises from the right coronary artery. It can be double or multiple and it provides blood supply to the superior aspect of the conus arteriosus region (outflow tract) of the right ventricle. It is also known as the “conus artery”, and the “infundibular artery”. In about 50% of the cases the conal artery arises separately from the aorta, very close to the ostium of the right coronary artery. In this case the artery has been dubbed the “third coronary”.
In many cases, a secondary conal artery arises from the anterior interventricular (LAD) artery and is called the “left conal artery”. In some cases this left conal artery can be the only one present and there may be no “right” conal artery. When both conal arteries are present, in some cases and evident superficial anastomosis can be seen forming what is known as the “conal ring” or the “ring of Vieussens”, one of the few cases where there is actual collateral circulation between the right and the left coronary arteries.
Sources:
1. “The clinical anatomy of the conal artery” Loukas, M el al. J Clin Anat 2014 DOI: 10.1002/ca.22469
2. “The Clinical Anatomy of the Coronary Collateral Circulation: Loukas, M, et al J Clin Anat (2009) 22:146–160
3. “The Normal and Abnormal Anatomy of the Coronary Arteries” Loukas, M et al J Clin Anat (2009) 22:114–128
4 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
5. "Anatomy of the Human Body" Henry Gray 1918. Philadelphia: Lea & Febiger
Image modified by CAA, Inc, Original image courtesy of bartleby.com