Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.
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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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The word [uncus] is of Latin origin and means "hook", or "curved". Its plural form is [unci]. In human anatomy we refer to hooked structures as "uncus". The the uncus of the pancreas is a hooked end segment of the head of the pancreas that curves around the superior mesenteric artery and vein. There is also the uncus of the parahippocampal gyrus, and others
The derivate root term [-unci-] gives us the adjectival form [unciform] meaning "with the shape of a hook". Applications of this root term include:
• Uncinate process of the pancreas
• Uncinate vertebral process, found in cervical vertebrae 3 to 7.
• Uncinate process of the ethmoid bone
• Uncinate gyrus, referring to the uncus of the parahippocampal gyrus
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UPDATED: The term [ligament] in the abdominopelvic region has a very different meaning from the term [ligament] referring to a tendon-like structure associated with a joint. This is one of the terms that is used in different locations with different meaning.
The term [ligament] in the abdominopelvic region refers to a fold of peritoneum over an underlying structure or to a reduplication of the peritoneum. This is extremely important, as most abdominopelvic "ligaments" have a content that could be endangered through surgical manipulation.
There are many ligaments in the abdomen and pelvis. Following is a list of some of them:
- Infundibulopelvic ligament
- Ligament of Treitz
- Falciform ligament
- Round ligament of the uterus
- Median umbilical ligament
- Suspensory ligament of the sigmoid colon, etc
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The superior mesenteric artery (SMA) is one of the anterior unpaired branches of the abdominal aorta. It is close to one centimeter in diameter at its origin and is about 15 centimeters in length. At its origin, just inferior to the celiac trunk, it is directed anteroinferiorly, hugged by the head and uncinate process of the pancreas. The SMA passes over the transverse (3rd segment) of the duodenum where it is accompanied by the inferior mesenteric vein.
The SMA provides supply to the duodenum, jejunum, ileum, the right side of the colon (cecum, vermiform appendix, and ascending colon), and the transverse colon. The jejunal and ileal arteries traverse within the layers of the mesentery.
As the SMA passes over the third portion of the duodenum, and because of the angle formed between the SMA and the abdominal aorta, it slightly compresses the duodenum. In very rare cases, this angle can be so acute as to cause duodenal obstruction requiring surgery. This rare syndrome is called “SMA compression syndrome” was first described in 1861 by Baron Carl Freiherr Von Rokitansky (1804 -1878). To see an article with a better image of the SMA-abdominal aorta angle click here.
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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.
Sir Astley Paston Cooper
Sir Astley Paston Cooper (1768 - 1841). An English anatomist and surgeon, Astley Cooper started his medical studies when he was only 16, at the St. Thomas hospital in London. He studied under Henry Cline, and later under John Hunter. Astley Cooper was a well-known anatomist, lecturer, and surgeon in his time. He is known for his many studies in abdominal hernia, otology, aneurysms, and the anatomy and diseases of the breast. In 1804 he described the abdominal transversalis fascia and the internal inguinal ring.
Born in the village of Brooke, Norfolk. At 16 years of age he was placed under the tutelage of Henry Cline (1750 - 1827), senior surgeon at the St. Thomas hospital in London for a seven-year apprenticeship. In 1789 he was appointed as an anatomy lecturer at the same hospital. In 1800 Cooper was appointed Surgeon to the Guy's Hospital in London.
He was the first to attempt the ligation of the abdominal aorta in a patient that had suffered an aortic abdominal aneurysm rupture. The patient survived for one additional day. "Astley Cooper introduced no new philosophy, policy or practice into surgery but was the perfect exponent of the scientific approach to surgery combined with skillful and successful practical ability" Brock (1969)
Cooper’s name survives in several eponymous anatomical structures and diseases he described, following are two of them:
• Cooper's ligaments of the breast: Connective tissue ligamentous strands between the pectoral fascia and the skin overlying the breast. (although it was first described by Andrea Vesalius).
• Cooper's pectineal ligament: A thickening of the periosteum on the superior aspect of the pubic bone, lateral to the pubic tubercle. This structure is a preferred site for staple positioning during a laparoscopic herniorrhaphy. When placing the staples, consideration should be placed on the potential presence of an anatomical vascular variation named the "Corona Mortis".
Although Cooper published a number of books and research papers, his seminal contribution to surgery was his two-volume "Treatise on Hernia". The first volume was published in 1795 and the second volume in 1807, with a revised second edition published in 1827.
Personal note: Although Sir Astley Cooper has been credited with the first description of the complex mammary suspensory ligaments (Cooper's ligaments), a 2016 paper by Brinkman and Hage (see Sources) contests this and gives Andreas Vesalius the honor of describing these structures nearly 300 years before Cooper! Dr. Miranda.
Sources:
1. "Sir Astley Paston Cooper." Singal, R. et al. Indian J Surg 73:1 (2011): 82-84.
2. "Sir Astley Paston Cooper, 1768-1841:the prince of surgery"Rawling, EG. Can Med Assoc J 99.5 (1968): 221.
3. "The life and work of Sir Astley Cooper" Brock, RC. Ann Royal Coll Surg England 44.1 (1969): 1-18
4. "Andreas Vesalius’ 500th Anniversary: First Description of the Mammary Suspensory Ligaments" Brinkman, RJ; Hage JJ. World J Surg (2016) 40:2144–2148
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The inferior vena cava (IVC) in one of the great vessels. It brings deoxygenated blood from the lower extremities, pelvis, and areas of the abdomen to the right atrium of the heart.
As a side note, the blood returning from the digestive system does not usually enter the IVC. It has it its own venous subsystem converging into the liver by way of the portal vein.
The IVC is formed by the confluence of the right and left common iliac veins. This lower end of the inferior vena cava is found anterior to the L4-L5 intervertebral disc. The IVC covers the superior aspect of the body of L5.
The IVC ascends to the right of the abdominal aorta and anterolateral to the vertebral bodies. It receives several branches as it passes superiorly:
• Common iliac veins
• Lumbar veins
• Gonadal veins
• Renal veins
• Right suprarenal veins
• Hepatic veins
• Inferior phrenic veins
As the IVC passes posterior to the liver, it is hugged by the mass of the posterior aspect of the liver, it will receive the hepatics veins, and pass through the IVC hiatus of the respiratory diaphragm, entering immediately into the right atrium of the heart. At this point the IVC will present an incomplete venous valve known as the Eustachian valve, named after Bartolomeo Eustachius (c1500 - 1574).
Sources:
1. "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 1995
3. "Reconstructive Anatomy: A Method for the Study of Human Structure: Arnold, M WB Saunders1968
Image modified from the original by Henry VanDyke Carter, MD. Gray's Anatomy.
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The pulmonary trunk is one of the great vessels of the heart. It is an artery that takes deoxygenated blood to the lungs as part of pulmonary circulation.
It starts proximally at the pulmonary semilunar valve. This valve is situated at superior end of the outflow tract of the right ventricle, an area called the conus arteriosus.
The pulmonary trunk has relation with the aorta on its right side, the left auricle and the left main coronary artery posteriorly. The pulmonary trunk is a short vessel, usually less than one centimeter in length. Most of the pulmonary trunk is found inside the pericardium. Almost immediately after it exits the pericardium it divides into a left and a right pulmonary artery, each one delivering deoxygenated blood to a lung.
It is a common misconception to call this vessel the "pulmonary artery". This is not correct, as the pulmonary arteries are the left and the right pulmonary arteries.
Sources:
1. "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 199
Image modified from the original by Henry VanDyke Carter, MD. Gray's Anatomy.