Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.
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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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BRRRRRRRR!!
A reminder of one of the joys of summer! The term [sphenopalatine ganglioneuralgia] is a fancy medical term for "brain freeze". which happens when we eat or drink very cold food.
The etymology of the term is complex. [Sphen-] is a term meaning "wedge" and refers to the sphenoid bone. [-palatine-] means "pertaining to the palate" (and to the bones related to the hard palate].
The root term [-gangli-] refer to a ganglion, which is a concentration of neuronal bodies, neurons being the main cells of the nervous system. [-neur-] means "nerve", and the suffix [-algia] means "pain". Simply said, the term [sphenopalatine ganglioneuralgia] means "nerve pain of the sphenopalatine ganglion".
The sphenopalatine ganglion (Meckel's ganglion, nasal ganglion or pterygopalatine ganglion) is a parasympathetic ganglion found in the pterygopalatine fossa. It is largely innervated by the greater petrosal nerve (a branch of the facial nerve); and its neuronal axons innervate the lacrimal glands and nasal mucosa.
Not everybody accepts this theory. Some state that "brain freeze" occurs because of rapid cooling of the blood in the pharynx, causing a drop of temperature of the internal carotid artery, which in turn causes cooling and pain in the meninges related to the base of the cranium.
My thanks to Gina Burg, for bringing this term to my attention. Dr. Miranda
Thanks to Forrest J. Bonjo for the image and additional information. The article was originally stored at pdu.edu, but the server was closed. If you click on the image, this will take you to the article stored at web.archive.org.
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There are many in the world that are fascinated by the life and works of Andreas Vesalius (1514 -1564). This has created a market for “Vesaliana”. These are books, art, medals, and works are related to Vesalius. As an example, an original 1543 Fabrica sells today for 400 thousand dollars! Even the “New Fabrica” by Drs. Garrison and Hast has cuadrupled its value in only two years since its publication!
Some of the most coveted items are stamps that celebrate the illustrious anatomist. Probably the most detailed research on the topic was made by Prof. Omer Steeno and Dr. Maurits Biersbrouck, both contributors to this website. Their research is constantly updated and the latest iteration of their work is “Andreas Vesalius in Philately” published in WordPress.com.
In a recent private communication Prof. Steeno regretted that unscrupulous individuals have taken to forge and falsify stamps. A clear case of this is the stamp collection “Les Grands Scientifiques de la Rennaissance” published in November 23, 2006 by the Republic of Djibouti. The stamps (shown in the accompanying image) depict Leonardo da Vinci, Nicolas Copernicus, Galileo Galilei, and Andreas Vesalius. As a Vesaliana collector, who would not want this set of stamps placing Vesalius in such company?
Djibouti is an African country that gained its independence from France in 2007 and is located in the horn of East Africa and the opening of the Red Sea into the Gulf of Aden.
Drs. Steeno and Beisbrocuk contacted the Djibouti postal service and were able to confirm in February, 2016 that indeed these stamps are false and collectors should be aware.
Sources:
1. “Andreas Veslius in Plhilately” Steeno, O; Biesbrouck, M 2016
2. Private communication. Steeno, O. 2016
3. “On the falsification of a Vesalius Stamp wrongfully ascribed to the postal service of Djibouti” Steeno, O; Biesbrouck, M 2016. EMediTheme 2016 Editor: Menzies, S.
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This is a series of articles on depression and published as a community service. The information in these articles follow our Privacy and Security Guidelines and cannot be construed as medical guidance. For additional information and counseling, consult with your physician or the appropriate health care professional of your choice. You can also find information on Transcranial Magnetic Stimulation (TMS) here. For the initial article on this series click here.
UPDATED: People with depressive pathology do not all experience the same symptoms. The severity, frequency, and duration of symptoms vary depending on the individual and his or her particular illness. Because symptoms are subjective, some patients will not express or hide them, making the diagnosis of depressive disorder difficult.
Following are the description of the symptoms by two different patients:
Patient 1
"It was really hard to get out of bed in the morning. I just wanted to hide under the covers and not talk to anyone. I didn't feel much like eating and I lost a lot of weight. Nothing seemed fun anymore. I was tired all the time, and I wasn't sleeping well at night. But I knew I had to keep going because I've got kids and a job. It just felt so impossible, like nothing was going to change or get better."
Patient 2
"I felt dirty and unwashed. All my surroundings felt dirty and I spent hours cleaning the house with no results. I took long baths and even after them I still felt dirty. My sleep was broken with horrible nightmares with gore and destruction. I felt tired, mostly because I could not sleep. I cried every morning because I felt like a total failure. I felt ugly and no amount of makeup could cover this feeling. I did not want to go out in public at all"
Signs and symptoms of depression may include:
• Persistent sad, anxious, or "empty" feelings
• Feelings of hopelessness or pessimism
• Feelings of guilt, worthlessness, or helplessness
• Irritability, restlessness
• Loss of interest in activities or hobbies once pleasurable, including sex
• Fatigue and decreased energy
• Difficulty concentrating, remembering details, and making decisions
• Insomnia, early-morning wakefulness, or excessive sleeping
• Overeating, or appetite loss
• Thoughts of suicide, suicide attempts
• Aches or pains, headaches, cramps, or digestive problems that do not ease even with treatment
Next article: Causes of Depression
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This is a series of articles on depression published as a community service. The information in these articles follow our Privacy and Security Guidelines and cannot be construed as medical guidance. For additional information and counseling, consult with your physician or the appropriate health care professional of your choice. You can also find information on TMS here.
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UPDATED: Everyone occasionally feels blue or sad. There are also those dreaded "winter blues". But these feelings are usually short-lived and pass within a couple of days, usually with no problems or persistent symptoms. Some people may even say that they are "depressed". Although this is true, that person is not clinically depressed.
When an individual has clinical depression, there are physical changes that happen within the brain which reflect in attitudes, mood, symptoms, and actions.
Clinical depression is a common but serious mental disorder that affects over 20 million people in the United States, many of which will never seek diagnosis or treatment. Patients present with depressed mood, loss of interest or pleasure, decreased energy, feelings of guilt or low self-worth, abnormal patterns of sleep or appetite, gruesome nightmares, and poor concentration. Moreover, depression may often come with symptoms of anxiety and varying complex presentations of bipolar disorder.
These problems can become chronic or recurrent and lead to substantial impairment in an individual’s ability to take care of his or her everyday responsibilities. At its worst, depression can lead to a patient's attempt on their life. Clinical Depression interferes with daily life and causes pain for both the individual, their families, and loved ones. Patients with depressive disorder often go from one job to another, cannot work, or eventually end in disability, being maintained by their family or loved ones.
Many people afflicted with Major Depressive Disorder (MDD) never seek treatment. This is specially true in males, where the World Health Organization (WHO) estimates that ”fewer than 25% of male sufferers worldwide will seek treatment because of the social stigma associated with mental disorders including depression.”
Properly and timely treated, even those with the most severe depression, can get better. Medications, psychotherapy, and electroconvulsive therapy (ECT) are the most common methods to treat depression. As patients move from one medication to the next level medication as well as augmentation medication, the annual cost for medication can be staggering, as well as the common, insidious, and problematic systemic side effects of both the drug therapy and ECT therapy.
The main objective of all treatments for MDD is to attain remission, but in many cases just reducing the symptoms of MDD and reducing the amount and types of medication used is enough to bring the patient back to a productive life and enhance the relationship with their families and loved ones.
Next article: Symptoms of Depression
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UPDATED: The definition of hernia is "the protrusion of a deep structure through a superficial weakness of defect".
Herniation has many etiologies, but in all cases a weakness of a superficial containing wall (usually layered) or a normal or abnormal opening (defect) must be present. A true hernia usually has a deep sac or hernia sac which contains the herniated viscus or viscera. Repair of a hernia is called a hernioplasty or a herniorrhaphy.
Although with exceptions, a herniation with only weakening of the walls and no hernia sac can be called a "prolapse", the suffix for prolapse (or hernia sometimes) is [-ocele].
• Omphalocele: From the Greek [omphalos] meaning "umbilicus", an omphalocele is a herniation through the umbilicus.
• Cystourethocele: A prolapse of the urinary bladder and urethra with a weakened vaginal wall
There are also "internal' hernias, between bodily compartments. Examples are:
• Esophageal hiatus hernia: Known as a "hiatal hernia", this hernia is a protrusion of a peritoneal sac with abdominal visceral content into the thorax.
• Perineal hernia: The protrusion of abdominopelvic content into the perineal region through a defect in the pelvic diaphragm (levator ani)
A hernia is usually named for the superficial region where it protrudes. An example of this would be a femoral hernia, which starts as an abdominopelvic extrusion, but it ends protruding in the area of the thigh (femoral region). Abdominal or ventral hernias are named according to the abdominal region through which they protrude.
in older times the word "rupture" was used as a synonym for "hernia", as can be seen in a letter written by Dr. Ephraim McDowell in 1829. The image shows an example of an indirect inguinal hernia.
Original Image public domain courtesy of: nih.gov.
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UPDATED: The word [pecten] originates from the Latin [pectine] meaning "to comb", the adjective [pectinate] means "resembling a comb". The term denotes structures that have well-formed parallel shapes, such as the pectinate muscle of the heart. The pectinate muscle can be clearly seen in the internal aspect of the atrial appendages. (see image, pointer "B")
The term [pecten] meaning "comb" is an old word used for the superior aspect of the pubic bone (os pubis) where the pectineus muscle attaches. The root term [-pectin-] can be seen then in terms such as the iliopectineal line, and the pectineal ligament, also known as "Cooper's ligament".
The origin of the use of the term [pecten os pubis] to denote the area of attachment of the pectineus muscle to the bony ridge in the superior aspect of the pubic bone is obscure, but the pectineus muscle has well-marked parallel striations resembling a comb.
The image shows a human heart where the right atrium has been opened. The red arrow points to the pectinated muscle characteristic of the right atrial appendage (right auricle). Keep in mind that the distribution and shape of the muscle of the left atrial appendage is completely different.
Note: The links to Google Translate include an icon that will allow you to hear the pronunciation of the word.